HMS Bristol was a 50-gun Portland-class fourth-rate ship of the line, built for the Royal Navy in the 1770s.

[1] Bristol, named after the eponymous port, was ordered on 12 October 1768 to a design by John Williams.

[2] During the American War of Independence, she was Commodore Sir Peter Parker's flagship during the attack on Sullivan's Island on 28 June 1776 and was heavily damaged during the battle.

On 21 May recaptured schooner "William" and captured sloop "Aurora", both off Bahia de Bueno Vista, Cuba.

After 1794 she was used as a prison ship (lying in Gillingham Reach, in the County of Kent),[4] and was broken up in June 1810 at Sheerness.