Clyde was the first ship built entirely in Portsmouth Naval base for 40 years and has been constructed alongside the bow and superstructure sections for the new Type 45 destroyers Daring and Dauntless.

[8] After being commissioned into active service Clyde was sent to the South Atlantic to relieve HMS Dumbarton Castle as the Royal Navy's patrol vessel in the area based in the Falkland Islands.

On 18 November 2015, Clyde assisted in the rescue of 347 passengers and crew from the cruise ship Le Boreal drifting off the Falkland Islands after an engine room fire.

[11] In January 2017, Clyde was dry docked in Simonstown, South Africa for maintenance;[12] her patrol duties were temporarily transferred to survey ship HMS Enterprise.

[13] In November, Clyde was redeployed from a patrol of South Georgia to assist in the search for the missing Argentinian submarine ARA San Juan.