HMS E49 was an E-class submarine built by Swan Hunter, Wallsend for the Royal Navy.

British E-class submarines had fuel capacities of 50 long tons (51 t) of diesel and ranges of 3,255 miles (5,238 km; 2,829 nmi) when travelling at 10 knots (19 km/h; 12 mph).

E49 was armed with a 12-pounder 76 mm (3.0 in) QF gun mounted forward of the conning tower.

[1] A memorial to the 31 submariners lost in the sinking of E49 was unveiled in Baltasound, Unst, on 12 March 2017.

The unveiling was attended by members of the crew of Royal Navy submarine HMS Vengeance (S31) and descendants of E49 First officer Basil Beal and second-in-command Reay Parkinson.