She sank two German submarines before she was transferred back to British coastal waters in May 1944 to protect the build-up for Operation Overlord.
Together with two other destroyers, she sank another German submarine that month and was reassigned to escort duties off the west coast of Scotland in July, where she remained until the war ended in May 1945.
The turbines developed a total of 36,000 shaft horsepower (27,000 kW) and gave a maximum speed of 35.5 knots (65.7 km/h; 40.9 mph).
Fame carried a maximum of 470 long tons (480 t) of fuel oil that gave her a range of 6,350 nautical miles (11,760 km; 7,310 mi) at 15 knots (28 km/h; 17 mph).
[5] Fame was ordered on 17 March 1933 from Parsons Marine Steam Turbine Company, although her hull was sub-contracted to Vickers Armstrongs.
Fame was initially assigned to the 6th Destroyer Flotilla (DF) of the Home Fleet, although she had to have her ammunition hoists modified at Devonport Royal Dockyard from 23 July to 28 August.
Fame was refitted at Devonport from 20 July to 10 November 1936 before she began to enforce the arms embargo imposed on both sides in the Spanish Civil War by the Non-Intervention Committee until January 1937.
The 6th DF was renumbered the 8th Destroyer Flotilla in April 1939, five months before the start of World War II.
A week later, she ran aground, together with the destroyer Ashanti, off Whitburn on the County Durham coast while escorting the battleship King George V. The ship was severely damaged and could not be refloated until 1 December.
Fame received temporary repairs at Sunderland before she was towed to Chatham Royal Dockyard on 2 February 1941.
The impact badly damaged the destroyer and she was forced to leave the convoy for repairs after rescuing 39 survivors.
[11] Fame was reassigned to patrol duty in the South-Western Approaches in May 1944 as part of the Normandy landings and became the senior ship of the 14th Escort Group.
Unlike most of the prewar destroyers, she remained on active duty and was assigned to the Rosyth Escort Force until October when she was transferred to the Londonderry Training Flotilla.