Chios was a Medea-class destroyer laid down for the Greek Navy by Fairfield Shipbuilding and Engineering Company, Govan in 1914.

The Greek Navy placed orders for two light cruisers and four destroyers from a syndicate of British shipbuilders and armament companies in late 1913–early 1914.

[5] The outbreak of the First World War resulted in the four under-construction destroyers being purchased by Britain for the Royal Navy in August 1914.

[6] The first of the two Fairfield-built ships, Melampus (which had been laid down as Chios) was launched at Fairfield's Govan, Glasgow shipyard on 16 December 1914 and was completed on 29 June 1915.

Melampus sighted C16's periscope, and attempted to take evasive action, but it was too late and the destroyer and submarine collided, sinking C16.

[20][21] Melampus was credited with the sinking of the submarine UC-16 on 22 October 1917, with Prize Money awarded to the destroyer's crew,[22][23] but UC-16 had probably been sunk in a British minefield off Zeebrugge earlier in the month.