[1] In September 1813, the commander-in-chief of British North America, Sir George Prevost approved further construction which was initially set to a brig, but was later revised to two frigates.

The construction of the vessel did result in the resignation of George Record, who was the master shipwright at Kingston and the frigate was built under private contract.

[7] Prince Regent was launched on 14 April 1814, a half hour after Princess Charlotte, the other frigate under construction.

[1][8][b] Prince Regent was made the flagship of Commodore Sir James Lucas Yeo's British squadron on Lake Ontario.

Commander Richard O'Connor was advanced to the rank of post-captain and made Yeo's flag captain aboard Prince Regent.

Following the disaster at Sandy Creek, the majority of the squadron, including Prince Regent, remained in Kingston's harbour for the remainder of the summer.

[10] The arrival of the first-rate, St Lawrence on Lake Ontario led to another round of command changes.

St Lawrence's arrival led Chauncey withdrawing his squadron to Sackett's Harbor and never returned in force to Lake Ontario for the rest of the war.

On 1 November, Prince Regent sailed as escort to a convoy transporting infantry reinforcements to Fort George.

[1] The wrecksite, along with those of St Lawrence and Princess Charlotte were designated a National Historic Site of Canada in 2015.