[2] On 4 April 2006, De Zeven Provinciën along with the destroyer USS Roosevelt responded to MV Dong Won which reported that it had come under rocket attack off the coast of Somalia.

[3] On 29 March 2009, as De Zeven Provinciën was part of Operation Atalanta, the German Navy tanker Spessart was attacked by 7-man pirate boat.

[10][11] On 9 October 2022, De Zeven Provinciën along with HNLMS Van Amstel deployed to conduct drills with the aircraft carrier USS Gerald R.

In November 2003, approximately 200 nautical miles (370 km; 230 mi) from the Azores, De Zeven Provinciën conducted her first live firings of these missile systems.

[14]Further live firings were performed by De Zeven Provinciën in March 2005, again in the Atlantic Ocean approximately 180 nautical miles (330 km; 210 mi) west of the Azores.

[14] The long-range SM-2 engagement apparently resulted in an intercept at a range of greater than 100 km (62 mi) from the ship, with a missile-target miss distance of 8 feet (2.4 m) (the warhead's proximity fuze having been disabled for the purposes of the test).

[14] On 24 October 2015 De Zeven Provinciën performed maritime integrated air and missile defense during a At Sea Demonstration (ASD).

[15] In May, 2021 during At Sea Demonstration/Formidable Shield 2021 De Zeven Provinciën detected and tracked a ballistic missile with SMART-L radar and relayed the target information to USS Paul Ignatius.