[citation needed] One notable organization that is supporting people with Hallermann–Streiff syndrome is the Germany-based "Schattenkinder e.V".

[1] Patients with this syndrome are shorter than the average person and may not develop hair in many places, including in the facial, leg and pubic areas.

Early measures are based around ensuring proper breathing and intake of nutrients and may include a tracheostomy.

Regular visits to an ophthalmologist to monitor and deal with other eye problems, some of which may require surgery, are strongly recommended.

[6] Management of the condition may also include surgical reconstruction of certain craniofacial malformations (particularly in the mandibular and nasal region) at an appropriate age.