The depot was on the main line of the Atchison, Topeka and Santa Fe Railway.

It was built in 1917 at a cost of $25,000, and was written in the Halstead Independent as "the most modern station that can be built... with steam heating, electric lights, toilets, sewer facilities... it is a station capable of meeting the needs of a town 10 times our size.

"[1] The depot closed in the early 1970s and by 1988 was planned to be demolished.

However, the Halstead Historical Society was formed that year for the specific purpose of saving the depot, and purchased the depot four years later.

[1] The station was added to the National Register of Historic Places on October 11, 2001.