Hamilton John Agmondesham Cuffe, 5th Earl of Desart, KP, KCB, PC (30 August 1848 – 4 November 1934) was an Irish peer and barrister.

[2] His paternal grandparents were John Cuffe, 2nd Earl of Desart, and Catherine, daughter of Maurice O'Connor.

In 1894, he was appointed a Companion of the Order of the Bath and as Treasury Solicitor that year, as well as Queen's Proctor and Director of Public Prosecutions.

In 1898, he inherited the earldom of Desart from his elder brother, William (who died without heirs male)[4] and was promoted as a Knight Commander of the Order of the Bath.

[7] On 19 July 1876, Lord Desart had married his second cousin, Lady Margaret Joan Lascelles (1853–1927), the second daughter of Henry Lascelles, 4th Earl of Harewood by his first wife, Lady Elizabeth Joanna de Burgh, daughter of Ulick de Burgh, 1st Marquess of Clanricarde.