The Hampden–Sydney Tigers are the athletic teams that represent Hampden–Sydney College, located in Hampden Sydney, Virginia, in NCAA Division III intercollegiate sports.

The Tigers compete as members of the Old Dominion Athletic Conference for all sports.

Hampden–Sydney sponsors 9 sporting activities for its male students.

"The Game" is often referred to as the oldest small-school football rivalry in the South,[2] with the first match up having been played in 1893.

Athletic events involving the two schools are fiercely competitive, and the week prior to "The Game" between Hampden–Sydney and Randolph-Macon is known as "Beat Macon Week".