The present Hampton Depot had its origins in 1873, when the superintendent reported at the annual meeting of the president and directors of the Central Railroad and Banking Company that the depot "at Hampton is entirely too small and insecure, and ought to be replaced by a larger and more substantial one at the earliest day possible."

In the superintendent's report of September 1, 1880, it was announced that "a new brick warehouse has been commenced at Hampton on the Atlanta division.

The Hampton Depot was unusual in that it included a warehouse for cotton in the same building with the passenger area.

The land is still owned by the railroad; the depot is now the "Glenn Mitchell Administration and Community Building."

The rooms off the park side of the depot, now house the Main Street Director, and a museum with items donated and on-loan from various residents of Hampton.