The women's handball tournament at the 2015 Pan American Games in Toronto, Canada was held at the Exhibition Centre (in Hall B) from July 16 to 24.

Brazil were the defending champions from the 2011 Pan American Games in Guadalajara, defeating Argentina, 33–15 in the final.

The winner of the tournament were to qualify for the 2016 Summer Olympics in Rio de Janeiro, Brazil, while the 2nd and the 3rd place (due to the continental rankings at the World Championship) qualified for the Olympic Qualification Tournament.

As the host nation Brazil won, the runner up qualified instead, in accordance with the regulations.

The fourth placed team in the Central American and Caribbean Games both declined to compete in the respective tournaments.