The CRC Handbook of Chemistry and Physics is a comprehensive one-volume reference resource for science research.

[2] As late as the 1962–1963 edition (3604 pages), the Handbook contained myriad information for every branch of science and engineering.

Earlier editions included sections such as "Antidotes of Poisons", "Rules for Naming Organic Compounds", "Surface Tension of Fused Salts", "Percent Composition of Anti-Freeze Solutions", "Spark-gap Voltages", "Greek Alphabet", "Musical Scales", "Pigments and Dyes", "Comparison of Tons and Pounds", "Twist Drill and Steel Wire Gauges" and "Properties of the Earth's Atmosphere at Elevations up to 160 Kilometers".

Later editions focus almost exclusively on chemistry and physics topics and eliminated much of the more "common" information.

CRC Press is a leading publisher of engineering handbooks and references and textbooks across virtually all scientific disciplines.