She is best known for her roles in Güneşin Kızları, Aşk Laftan Anlamaz, Halka, Azize, Sen Çal Kapımı y Bambaşka Biri Hande Erçel starred in the series Aşk Laftan Anlamaz (2016–2017) as Hayat Uzun, opposite Burak Deniz.
The show gained her and Deniz wide popularity, especially in the Middle East, as well as India, Pakistan and Uzbekistan .
[2] She also played the role of Hazal in Siyah İnci on Star TV.
[3] In 2020, Erçel was cast as a leading role in Sen Çal Kapımı, which opened with high ratings in Turkey.
[4] In 2023, Erçel was cast alongside Burak Deniz for the second time in Bambaşka Biri, which aired for 16 episodes and won a Rose D'Or award.