"Hands Off" is a 1955 song written and recorded by Jay McShann.
The single, on the Vee-Jay label, was the most successful Jay McShann release on the Billboard R&B chart.
"Hands Off", with vocals performed by Priscilla Bowman, was number one on the R&B best seller chart for three weeks.
For the next twenty-one years, all singles which made the top spot on the Billboard R&B chart would make the pop charts.
[1] Preston Foster reworked "Hands Off" to create the 1956 song "Got My Mojo Working"[citation needed] popularised by Muddy Waters.