Hankou railway station (simplified Chinese: 汉口站; traditional Chinese: 漢口站; pinyin: Hànkǒu zhàn) is one of the three main railway stations in the city of Wuhan, the capital of Hubei Province of the People's Republic of China.

Hankou railway station became connected to Wuhan Metro on 28 December 2012, with the opening of Line 2 of the city's subway system.

The station's location near the Huanan Seafood Wholesale Market may have contributed to the spread of the Coronavirus disease 2019.

[2][3] On 23 January 2020, the station was closed, along with all other transport infrastructure in the city in the 2020 Wuhan lockdown caused by the outbreak of COVID-19.

After the completion of the high-speed Hefei–Wuhan railway from Hefei in April 2009, the Hankou Station became the main Wuhan terminal for the high-speed trains arriving to the city on this line from Shanghai via Nanjing and Hefei, although as of December 2013 at least three of these trains arrives to the Wuhan railway station instead, and some go to Wuchang.