In 2004, she received a MA in international journalism at Lviv University, a PhD in Social Communications in 2009 and a CEP Diploma for achievements in ecological teaching from the Civic Education Project.

[13] Hopko has contributed to various training programs for civil society activists in Ukraine, Kazakhstan, the Kyrgyz Republic, Georgia, and Belarus.

From 2005 to 2007, she worked as communications manager of the Ukraine Citizen Action Network (UCAN/ISC, USAID contractor) in Kyiv, and led environmental journalism training programs in Donetsk Oblast, Belarus and Kazakhstan.

In 2009, she co-founded the Life Regional Advocacy Center, Ukraine's primary partner of the Bloomberg Initiative to reduce tobacco use, and the Ukrainian representative of ENSP, FCA and WHO.

[17][18][19] She led the National Interest Advocacy Network, and the International Center for Ukrainian Victory, organizations that support Ukraine and its people on an individual, community, and global level.

[20] Since Russia's invasion of Ukraine on February 24, 2022, Hopko, together with other Ukrainian civil society leaders Daria Kaleniuk, Olena Halushka, Olga Aivazovska as well as Katarzyna Pisarska Fundacja im.

[25] In February 2022, ICUV began the Block Putin Wallets campaign, pushing Western governments to confiscate Russian oligarchs' assets.

[26] Hopko also defended Ukraine's interests during a visit to South Korea, speaking at a round table organized by Human Asia and the Transitional Justice Working Group in Seoul in November 2022.

[27][28] In January 2023, under the MOUs signed with Hopko, Mykolaiv Mayor Oleksandr Syenkevych and Kherson сivil–military administration, Taiwan donated US$ 1 million to the three cities to purchase generators and heating equipment.

These objects will be accomplished by implementing and promoting necessary reforms, fighting corruption, especially in the face of Ukrainian oligarchs, and countering russian aggression in its hybrid form.

On 31 August 2015, Hopko and four other MPs of the Self Reliance party voted in support of amendments to the Ukrainian Constitution that would implement decentralization reform in Ukraine.