She was one of the first high-profile female nationalists in the movement,[2] and was the National Propaganda Secretary for the Convention People's Party.

[8] The marriage did not last, and she began living with her brother, E. K. Dadson, a prominent United Gold Coast Convention (UGCC) activist.

This happened shortly after he had returned to Ghana in 1947 from studying abroad in the United States and Britain for over a decade in order to take up the position of general secretary of the United Gold Coast Convention, a political party formed by George Paa Grant to fight against British colonialists and grant Ghana its independence.

[2]After that encounter with Kwame Nkrumah, she subsequently become a key supporter of the United Gold Coast Convention (UGCC) began raising support for the UGCC, to the extent that when the Big Six were arrested, Kudjoe raised funds and led a campaign for their release.

[10] Kudjoe was also an active participant of the Positive Action, a campaign of mass civil disobedience coupled with political protests that eventually led to the end of colonial rule, Nkrumah's election victory and the formation of an independent nation.She inspired massive support for the CPP through this campaign.

[11] In that role she toured the country advocating the need for independence and organizing rallies propagating the Nkrumah movement and the CPP.

[9] Whilst working in her official roles with the CPP in the 1950s and 1960s, Kudjoe was also undertaking social welfare works within the Northern regions of Ghana teaching both young women and adults basic life skills in hygiene, home keeping, dressing and how to raise children.

[13] After Kwame Nkrumah was overthrown by the military on 24 February 1966, Kudjoe left the political scene like every CPP member and returned to her private life.

[11] Her final scene in the public domain was when she addressed an International Women's Day symposium at the Accra Community Centre on 8 March 1986, a night before she died.

[14] Her obituary published on 8 May 1986 ends: "She was a priceless gem who in no small measure contributed to the political emancipation of Ghana from the clutches of imperialism.