Hanequin de Bruxelles (Flanders, unknown date – Toledo, 1494) was a 15th-century Flemish architect and sculptor.
He worked alongside his brother Egas Cueman on the chapter house of Cuenca Cathedral in 1454.
This is a unique castle of its type due to its exterior aspect which has nine curtain walls and six slight towers that seem to form pincers.
In 1465 he appeared with his son, Hanequin de Cuellar, in Cuellar to carry out the renovations and extensions of the castle of Beltrán de la Cueva, Duke of Albuquerque, who had taken possession of the village for the first time a year before.
Albuquerque wanted to reinforce the construction because of Isabella I of Castile's views on the ownership of Cuellar.