After World War II, the British military government in Allied-occupied Germany wanted to hold a trade fair and sought for a good place, since Leipzig, the traditional fairground of Germany, was unavailable, being in the Soviet occupation zone.
During the large fairs, like CeBIT or Hannover Messe, there is a special peak hour express service, denoted by the letter E, which only stops at the stations Hauptbahnhof, Kröpcke and Aegidientorplatz.
The railway station is named Hannover Messe/Laatzen after the suburb of Laatzen, which has a common border with Hanover near the fairground.
It is only notably used during CeBIT, Hannover Messe and Agritechnica, and outside of this period, only regional services stop at the station.
Since December 2008 the station has been connected to the Hanover S-Bahn, the city's suburban railway system.