[1] Müller-Wohlfahrt was born as the third son of pastor Diedrich Müller and his wife Elisabeth, née Pape, in Leerhafe, which is today part of Wittmund, East Frisia.

[8] In November 2008, Müller-Wohlfahrt took a temporary leave from his duties but returned to the Bayern Munich bench after the dismissal of coach Jürgen Klinsmann in April 2009.

[2] On 16 April 2015, Müller-Wohlfahrt and his medical team ended their cooperation with Bayern Munich, citing a damaged trust relationship with then-coach Pep Guardiola.

[11][12][13] In April 2007, Müller-Wohlfahrt co-founded MW Orthopedic Centre GmbH, establishing a center for sports medicine in an exclusive location in Munich.

In April 2010, Dietmar Hopp's private company acquired all the shares of MW Orthopedic Centre GmbH, and since then, Müller-Wohlfahrt has continued to practice there as a tenant, lending his name to the facility.

[14][15][16] Müller-Wohlfahrt is known for his controversial treatments, including the use of Hyalart (sodium hyaluronate),[17] Actovegin (a hemodialysate from calf's blood),[7] and Myo-Melcain (Procaine in a honey solution).