[2] In 1984, the Bostoner Rebbe, Grand Rabbi Levi Yitzchok Horowitz, decided to establish a center in Har Nof in Jerusalem, which was instrumental in building up the neighborhood's Orthodox community.

The campuses of Neve Yerushalayim and She'arim College of Jewish Studies for Women are located in Har Nof,[9] as is Yechaveh Da'at, Rabbi Ovadia Yosef's synagogue and spiritual headquarters.

Two Arab terrorists from East Jerusalem entered the synagogue with knives, a meat cleaver, and a pistol, inflicting heavy wounds on their victims who were at morning prayers, killing five and injuring eight - four of them seriously.

The residents of Har Nof founded Shomera, a non-profit environmental protection association to thwart the building of high-rise luxury towers that would block the view of the Jerusalem Forest.

[15] Em Habanim is a volunteer organization founded in 1995 by Malka Yarom, a Har Nof resident who opened her home to religious divorcees who had nowhere to take their children on the Sabbath.