Harmodio Arias Madrid (3 July 1886 – 23 December 1962)[1] was a Panamanian politician.

He served as acting President of Panama in January 1931 and again from 5 June 1932, to 1 October 1936, after winning the 1932 presidential election.

His brother Arnulfo Arias was president on three occasions.

Harmodio's son, Roberto was a diplomat and politician who married the English ballerina Margot Fonteyn.

However, he returned to office after winning the popular vote in 1932.