Lyman Beecher accepted a job at Lane Theological Seminary in the Walnut Hills area of Cincinnati, founded in 1830.

The company included her father, her stepmother, her aunt Esther, her siblings Catharine and George, and half-siblings Isabella, Thomas, and James.

[8] Catharine, Harriet's older sister by eleven years, established the Western Female Institute in town.

Henry Ward Beecher was an early leader in the women's suffrage movement and a popular Protestant minister.

It is located in the Walnut Hills neighborhood (Martin Luther king exit from Interstate 71) at 2950 Gilbert Avenue, Cincinnati, OH 45206 and is operated by volunteers with the Friends of the Harriet Beecher Stowe House, Inc.

It is open to the public, located in small park, and operated as an historical and cultural site, focusing on Stowe and her family, the Lane Seminary, abolitionists, and the Underground Railroad.