Harris Hill is a hamlet and census-designated place (CDP) located in the town of Clarence in Erie County, New York, United States.

The region is named after Asa Harris, a former officer in the American Colonial Army, who established a tavern near the top of a low hill northeast of Buffalo.

According to the United States Census Bureau, the CDP has a total area of 4.0 square miles (10 km2), all land.

Just to the southeast of Harris Hill, is a large crushed stone quarry located in the town of Lancaster.

Buffalo Crushed Stone is located on the south side of Wehrle Drive, just east of Harris Hill Road in Lancaster.

Freed slaves would sneak under Main Street (present-day NY Route 5) through limestone caves and exit north at the bottom of the Onondaga Formation into a swampy forest.