The club lasted one year before moving to the New York State League and playing as the Harrisburg Islanders before disbanding in 1917.
The original Harrisburg Senators' reign ended in 1936, when flood waters from the surrounding Susquehanna River ruined their home ballpark, Island Field.
Another Senators team, representing Harrisburg and affiliated with the Pittsburgh Pirates, formed four years later in the smaller Interstate League.
Like the Senators before it, the team gained success quickly, winning the league title one year later with stars Billy Cox and Dennis Taylor.
The Interstate League disbanded this Harrisburg team in 1952, and any form of professional baseball was not played in the city for the next 35 years.