Harrison Center is a community-based arts nonprofit based in the Old Northside Historic District of Indianapolis, Indiana, United States.

The gothic revival building was originally constructed as the fourth home of First Presbyterian Church, designed by architectural firm Cropsey & Lamm.

[2] President Benjamin Harrison was a notable congregant, elder, and Sunday school teacher at First Presbyterian for forty years.

[10] These services included a thrift store, food pantry, adult day care, preschool, and methadone clinic.

[11] In 2000, local philanthropist Jeremy Efroymson bought and stabilized the neglected 65,000-square-foot campus before establishing the “Harrison Centre'' as a for-profit studio center.

[19] The following year, HC retained the Indianapolis 500 as a partner in the endeavor, expanding Porch Party Indy’s coverage to the entire state.

[23] In 2018, HC established the Greatriarch Program, promoting increased engagement and dialogue with long-term residents of the Martindale-Brightwood neighborhood.

The grant went towards the fulfillment of the “Convertible” project, which saw the implementation of creative programming initiatives in an effort to make the center more approachable to a wider audience of art patrons.

[25] This included the addition of a karaoke elevator, LED tetherball, an adult-sized slide, a human-sized hamster wheel, various light installations, and special programming.