[4] Harry S Truman High School has historically offered the various Advanced Placement (AP) level classes, including U.S. history, U.S. government and politics, chemistry, English literature, statistics, and calculus AB (though BC has been offered to particularly advanced students).

HST won an AP Honor Roll award for their distinguished scholars for the years 2011-2012, besting other school districts in the area.

It also has an English as a Second Language (ESL) program and often hosts international students who are studying abroad in the United States.

Harry S Truman HS was a pilot school for the United States Navy's Junior Reserve Officers Training Corps program.

Truman's drama program was led by Louis Volpe for about 45 years until his retirement in June 2013.

In October 2012, the Bristol Township School Board approved a resolution that would name Truman's auditorium after Volpe.

[5] Author Michael Sokolove wrote the book Drama High, which focuses on the life of Lou Volpe and history of the Truman theater program.

Tyrone Lewis graduated from Truman, where he was senior class president and record-setting basketball player.