He spent most of his club career in the Swiss Super League, playing for Lausanne, Young Boys, Servette, and Aarau.

Vardanyan was also a key defender for the Armenia national football team, having played 62 international matches.

Harutyun Vardanyan was born in Leninakan (now Gyumri), but began his career as a football player in Lori Vanadzor.

Vardanyan stayed at Fortuna Köln for two seasons, then returned to Switzerland and played for Young Boys Berne.

In early February 2005, Vardanyan was injured in a test match between Aarau and FC Seoul, which left him out of football for six months.

[4] On 29 August 2005, in part to match against the Netherlands and the Czech Republic for the first time after a long break caused by trauma, figured Vardanyan.

Jean-Marc Hofstetter, President of FC Biel Bienne, for which at the time Vardanyan played for, was surprised by the event.