After graduation, he moved back to Oslo where he began working with the Norwegian Refugee Council (NRC) in 2002[10] at their headquarters as a coordinator for their readiness forces.

[17] The UN letter, dated 17 February 2016, showed investigators raised concerns over Khaire's possible links to extremist groups after obtaining his "electronic contact list", which it analysed with the cooperation of an unidentified UN member state.

[21] Prior to his appointment, Khaire had never held public office, although over the course of his career he has worked with a range of high-level executives and government officials in various capacities.

[23] He also vowed to tackle corruption by prosecuting individuals involved, regardless of their position, and chaired his first official Cabinet meeting, he reminded the gathered Ministers of his and their duties as statesmen, noting that the administration's focus should be on strengthening the security sector, accelerating institutional reform.

[23] On 25 July 2020, the Speaker of the House of the People of the Federal Parliament, Mohamed Mursal, announced in a press statement that 170 MPs had withdrawn confidence in Khaire's government, accusing the Prime Minister of failing to deliver promises including improving the national security and implementing a timely one person, one vote election.

[26] The Embassy of the United States in Somalia has expressed concern over the "irregularities" of the voting process[27] and the High Representative of the European Union, Josep Borrell, has released a statement regretting that the motion of no-confidence did not meet the constitutional requirements.

[29] After his return to Mogadishu, he released a short statement calling the process of the motion of no-confidence unconstitutional and offering his resignation to "set a good example in leadership" and to ease the tensions.