The strip centers on a young girl, named Heart, who lives in Philadelphia.

[2] In the strip for April 6, 2020,[10] Tatulli acknowledged the Coronavirus pandemic and its "social distancing" mandates (in the form of wearing Star Wars helmets to the grocery store), one of the first daily comic strips to do so.

[11] On April 27, 2020, Mark Tatulli handed over the strip to a new artist, Christina "Steenz" Stewart.

Their first strip, appearing that day, established that Heart and Dean were now in middle school.

The series will be a co-production between Andrews McMeel Publishing and Canadian animation Slap Happy Cartoons.