An EDM and pop song with dance-pop influences, it was co-written by Guetta, Galantis member Christian Karlsson, alongside Perrie Edwards, Leigh-Anne Pinnock, and Jade Thirlwall.

"Heartbreak Anthem" received positive reviews from music critics, with praise being drawn to its uplifting good vibe and group vocals.

Galantis, David Guetta, and Little Mix began work on "Heartbreak Anthem" before the COVID-19 pandemic, and between London, Los Angeles and Stockholm.

As many collaborations have gone in these times, it was a remote work in progress for months, with stems sent back and forth from London to Los Angeles to Stockholm to Paris.

[9] "Heartbreak Anthem" was written by Perrie Edwards, Leigh-Anne Pinnock, Jade Thirlwall, Jenna Andrews, Thom Bridges, Henrik Jonback, Lorenzo Cosi, David Saint Fleur, Johnny Goldstein, Yk Koi, Sorana Păcurar Christopher Tempest, alongside David Guetta, and Christian Karlsson, who produced the track.

[14] DJ Times' Brian Bonavoglia stated the collaboration as an "uplifting sing-a-long that is impossible not to fall in love with".

"[17] From Official Charts, Rob said "The whole thing eventually builds into a frothy and ridiculously bouncy affair laced with Galantis' signature string-flecked EDM flourishes and Guetta's dependable dance pop production.

The music video features Little Mix members in theatre production, and opens up with the group dressed as winged angels, each having a microphone accompanying them.

[42] Samuel Douek in an Instagram post said "The concept of the video is inspired by Angela Carter's infamous 1984 novel Nights at the Circus, a magical realism feminist tale about freedom".

Douek stated that "The video touches upon the pressures of fame and heartbreak, evoking a message of self-acceptance against the backdrop of a sci-fi burlesque world".

[44] From ThatGrapeJuice, Sam Ajilore applauded the music video and stating the song is "rich in summer smash potential".