McComb started acting at age two in a commercial for Publisher's Clearing House.
In 1989, she played the title character in Francis Ford Coppola's segment, "Life Without Zoë", of the anthology film New York Stories.
When she appeared in the telefilm Generation X in 1996, she became the first actress to portray the X-Men character Jubilee on screen.
[citation needed] On July 5, 2003, McComb married actor James Van Der Beek.
They separated in April 2009,[1] and on November 20, 2009, Van Der Beek filed for divorce.