Mitchell is a graduate of the National Institute of Dramatic Art, and has performed on stage since 1975, including collaborations with dance company Force Majeure.

[citation needed] Other television productions she has appeared in include: the miniseries Bodyline (1984), Land of Hope (1986), Embassy (1992) and A Country Practice.

[citation needed] In 2024, Mitchell was named as one of the cast for the miniseries The Narrow Road to the Deep North,[1], and she played Margaux in the Paramount Plus series Fake.

[5][6] Never Did Me Any Harm (Sydney Festival, January 2012), exploring parenting, was a joint production between STC and dance company Force Majeure.

It starred Mitchell, Marta Dusseldorp, and Vincent Crowley, with a solo dance performed by dancer Sarah-Jayne Howard.

[7][8] Mitchell co-wrote the script of Force Majeure's You Animal, You with artistic director Danielle Micich, which explored the sense of smell.