Hedwig of Munsterberg-Oels (Czech: Hedvika Minstrberská; 10/12 June 1508, Oleśnica – 28 November 1531, Legnica) was born Duchess of Münsterberg and Oleśnica and Countess of Kladsko and by marriage Margravine of Brandenburg-Ansbach-Kulmbach.

Hedwig was a daughter of Duke Charles I of Münsterberg-Oels, who was a grandson of the King George of Bohemia.

Her mother was Anna of Sagan, a daughter of John II, the last Duke of Żagań (Sagan).

On 9 January 1525 Hedwig married George, Margrave of Brandenburg-Ansbach-Kulmbach.

The marriage produced two daughters: Hedwig died in Legnica (Liegnitz), where she was buried.