[4] Schreck's first play, titled Creature, debuted in New York and was directed by Leigh Silverman and produced by New Georges and Page 73.

[5] Schreck has also written episodes of the TV series I Love Dick, Nurse Jackie, and Billions.

[4] The play was picked up as a movie directed by Marielle Heller for streaming by Amazon and released in time for the 2020 Presidential elections.

Schreck has performed Off-Broadway in, among others, Drum of the Waves of Horikawa (HERE Arts Center, 2007)[9][10] and Circle Mirror Transformation (2009) and How the World Began (Women's Project, 2011)[11] at Playwrights Horizons.

[14] Schreck and the cast of Circle Mirror Transformation received a 2010 Drama Desk Award, Outstanding Ensemble Performance.

The award is presented to an American author honoring a work "dealing with social, political or religious mores of the time".

[25] On April 25, 2024 she spoke as part of a pro-ERA panel alongside Gloria Steinem and Carol Jenkins after a performance of the musical Suffs.