Following production of the last episode of Just the Ten of Us in 1990, Zeigler made several guest appearances on various television shows before she was cast in her first feature film, There Goes the Neighborhood (Paramount Pictures, 1992).
Playing the part of "Swan Babitt", she was a supporting actress as a member of the film's (Jeff Daniels, Catherine O'Hara, Héctor Elizondo, Chazz Palminteri, Rhea Perlman, Dabney Coleman).
Just months after the production concluded, Zeigler was cast as a series regular on Fox Television's Drexell's Class (starring Dabney Coleman).
Playing the role of "Nicole Finnigan", an elementary school student in Mr. Drexell's class, Zeigler's co-stars also included Jason Biggs, Matthew Lawrence, Brittany Murphy, and A. J. Langer.
Heidi Zeigler declared her retirement after Drexell's Class was cancelled in 1992, citing her desire to attend public school.