[1] Born in Prague, after his secondary school studies, Mache completed the first year of physics in Prague, among other things, heard lectures by Ernst Mach and in 1894 moved with his family to Vienna, where he continued his studies with Franz Serafin Exner and continued with Ludwig Boltzmann.

In connection with his research he conducted air electrical measurements on the Red Sea, in Delhi, Ceylon and Upper Egypt.

In 1966 in Donau City (22nd District), Vienna, the Makegasse (Mache Alley) was named in his honor.

Due to his work with radon, the now unusual unit Mache was named for describing the activity of radioactive medicinal waters.

Mache continued the Zippermayr Group experiments with early Carbon-Oxygen Fuel–air explosives, which SS sought to develop in Austria during the WWII, under the Soviets in late 1945.