In his career, Pereira has recorded with the band Simply Red and several famous musicians, such as Elton John, Rod Stewart, k.d.
Although primarily a guitarist, he also provided backing vocals live for the Simply Red song "Thrill Me".
He also collaborates with film directors Chris Renaud, Pierre Coffin, Kyle Balda, Raja Gosnell, and Cal Brunker.
In 1994, he released a solo album in the UK called Heitor TP, which featured guest appearance from Mick Hucknall on the track "Manchester".
In 2006, Heitor Pereira won a Grammy Award for 'Best Instrumental Arrangement Accompanying a Vocalist' on a version of the song "What Are You Doing the Rest of Your Life?"