The Spanish Colonial Revival building was built in 1926 based on a design by architect C.E.

The branch was named for 19th Century American author Helen Hunt Jackson whose popular novel Ramona told the story of a romance between a mixed-race girl and an American Indian during the days of the California missions.

The new building for the Jackson Branch was built at 25th Street and Naomi Avenue opened in November 1925.

At the time of the opening, the Los Angeles Times wrote: "Noerenberg, the architect, ... has succeeded in combining in this new library ample window lighting with sufficient wall and shelving space together with an attractive exterior.

[4] As of May 2008, the building was used as a church operated by the "Asamblea Apostolica de la Fe in Cristo Jesus", as shown in the photograph above.