As a teaching hospital, its affiliated to the University of Witwatersrand's Medical School.

[1]: 133  The hospital would be renamed 1 April 1997, after anti-apartheid activist Helen Joseph.

[1]: 133  In 2022 it was described as a delinquent rate payer, when it was over R44 million in arrears with its municipal bills.

[4] The hospital is affiliated with the University of Witwatersrand's Medical School and responsible for the teaching of healthcare workers and providing tertiary health services the Johannesburg community.

[2] The Thembalethu Clinic opened in 1992 and treats patients diagnosed with HIV, Aids and Tuberculosis.