Helene Weber (born 17 March 1881 in Elberfeld, now Wuppertal, Rhine Province, died 25 July 1962 in Bonn) was a German politician and was known as a women's rights activist.

After several years teaching in Elberfeld, she matriculated at the University of Bonn and later at Grenoble to study history, philosophy and Romance languages.

In March 1933, she joined the former Reich Chancellor Heinrich Brüning among the minority of Centre MPs who opposed Hitler's Enabling Act.

Ultimately, however, she bent to pressure from the Reichstag Group and agreed to the law, which was a decisive step along the road to power for the Nazis.

After the Nazi takeover, she was forced into early retirement on political grounds as of 30 June 1933 and subsequently worked in social welfare on a volunteer basis.

In 1948 she was elected in the Parliamentary Council to serve as one of four women involved in drafting the constitution of the Federal Republic of Germany project.

In the fourth legislature Helene Weber was third oldest member of the Bundestag after Konrad Adenauer and Robert Pferdmenges.