It is the only wing within the German Air Force whose weapon systems consist solely of helicopters.

Until 1 January 2013 the wing flew predominantly Bell UH-1D which were to be replaced by helicopters of the type NH90.

[8] Whereas helicopter units of the German Army Aviation Corps have been deployed in a variety of military missions abroad, mainly as part of KFOR in Kosovo and ISAF in Afghanistan, Helicopter Wing 64 had not been brought into action outside Germany until 2013.

However, only weeks after having been established, the wing provided disaster relief when the river Black Elster burst its banks, resulting in dam failures, which caused widespread flooding in Bad Liebenwerda, Löben and the surrounding areas in September and early October 2010.

[10] German Army Aviation Corps Medium Transport Helicopter Regiment 25 flying CH-53G, based at Laupheim Air Base, was disbanded on 31 December 2012 and re-established as new Helicopter Wing 64 on 1 January 2013.

Holzdorf Air Base was utilised as hub for all aerial rescue and support operations at the rivers Elbe, Saale, Mulde, Black Elster and White Elster as well as near Bitterfeld and in Fischbeck.