Founded in 1967 following the acquisition of the professional license of RKSV Helmondia '55 [nl], the club achieved promotion to the top-tier Eredivisie in 1982.

The club's most notable achievement came in the 1984–85 KNVB Cup, where they finished as runners-up after a narrow defeat to FC Utrecht in the final.

[4][3] In its early years, Helmond Sport struggled to make a significant impact in the Eerste Divisie, achieving only three top-ten finishes in its first 13 seasons.

[7] The match, played in Utrecht due to financial considerations, ended in a 1–0 defeat for Helmond Sport after John van Loen scored in the final minute.

Improvement came in the 2016–17 season under new head coach Roy Hendriksen, as the team secured a spot in the promotion play-offs by finishing second in the second period.