Henderson is an unincorporated community and former town in Mason County, West Virginia, United States, at the confluence of the Ohio and Kanawha Rivers.

The town was incorporated in 1893 and named for Samuel Bruce Henderson, who owned the townsite at the time.

[6] Located near Henderson is the General John McCausland Memorial Farm, listed on the National Register of Historic Places in 2003.

[8] The climate in this area is characterized by relatively high temperatures and evenly distributed precipitation throughout the year.

33.3% of all households were made up of individuals, and 8.8% had someone living alone who was 65 years of age or older.

There were 149 housing units at an average density of 338.6 per square mile (130.7/km2).

23.9% of all households were made up of individuals, and 11.2% had someone living alone who was 65 years of age or older.