The team is a member of the Great American Conference which is in the Division II of the National Collegiate Athletic Association and are currently coached by Scott Maxfield, who is in his seventh year at the university.

[2] Henderson State shares the longest rivalry in Division II football with Ouachita Baptist Tigers, the Battle of the Ravine, which began in 1895.

Gus Malzahn, deemed the father of the Hurry Up, No Huddle offense played wide receiver for the Reddies, and is one of their most famous alumni.

Sporty Carpenter is the leader in seasons coached and games won, with 119 victories during his 19 years at Henderson.

Hendrix College, then known as the Bulldogs, was Henderson's main athletics rival during its early years (1905-1929).