Built in 1736 by Henry Antes, it is a particularly high-quality example of a Moravian settlement house, with intact original interior finishes.

It was designated a National Historic Landmark in 1992,[2][3] and is now operated as a museum by Goschenhoppen Historians, a local preservation group.

The Henry Antes House stands in a rural setting, roughly midway between Pottstown and Perkiomenville on the south side of Colonial Road a short way east of its crossing of Swamp Creek.

The house is unusual because so much of its original interior finish, including ceilings and board partition walls, have survived.

In the American Revolutionary War, the house served as headquarters for General George Washington, September 23 to 26, 1777, during the Philadelphia Campaign.