He invested in iron furnaces north of the city, which prompted a move to Crawford County, Pennsylvania, of which he was elected the newly formed jurisdiction's first district attorney and served from 1799 to 1801.
He was elected to the United States Congress as a member of the Democratic-Republican Party in 1816, representing Pennsylvania's 14th congressional district; he was reelected twice, but resigned in May 1822 due to poor health.
In 1828, Jackson rewarded his political services in Pennsylvania and advisory role in the presidential campaigns of 1824 and 1828 by nominating him to the cabinet post of Secretary of the Treasury.
Jackson's first attempt at nomination was blocked in the Senate by then Vice President John Calhoun, largely because of Baldwin's strong position in favor of high-tariff policy.
When Bushrod Washington died after thirty-two years of service on the Supreme Court, the president appointed Baldwin to replace him.
449 (1841), Justice Baldwin emphatically expressed his opinion that, as a matter of constitutional law, slaves are property, not persons.
He wrote of Marshall that "no commentator ever followed the text more faithfully, or ever made a commentary more accordant with its strict intention and language."
A case that demonstrates Baldwin's admittedly inconsistent record of writing opinions and political boldness, as well as his unique style of jurisprudence is Worcester v. Georgia (1831).
Samuel Worcester and Elizur Butler, two missionaries who had been living with the Cherokees, were arrested in March 1831 for violating that statute.
The court issued its decision on March 3, 1832, that the Georgia statutes were unconstitutional as applied to the Cherokee tribes.
He agreed with Justice Marshall's opinion exclusively on his holding that the Cherokees were a sovereign nation "which this court is bound to judicially know as such to have and possess a jurisdiction over the lands they occupy."
Continuing his dissent, Baldwin ruled that the "national existence of the Indian tribes," according to the Constitution, was subject to the power of Georgia "by her own right and the Compact of 1802.
As part of its anti-Worcester campaign, the principal press organ of the Jackson administration published Johnson's anti-Cherokee concurrence in Cherokee Nation v. Georgia and promised to follow with Baldwin's Worcester dissent.
Referring to the Court Report and an article published by the Washington Globe on March 3, 1832, one scholar concludes that the non-disclosure of his dissent is indicative of Baldwin's awareness of the tense political climate over states' rights at the time.
The facts of the case include that John W. Brown, in Mississippi, purchased slaves from Slaughter of Louisiana.
[8] Groves contended that the Mississippi Constitution of 1832, which prohibited the importation of slaves merchandise after May 1, 1833, voided the note.
[8] In a concurring opinion, Baldwin opposed Taney and McLean's concurrences on questions about the commerce clause that were not needed to resolve the case.
Chief Justice Taney had written separately to state that the importation of slaves "cannot be controlled by Congress".
He acknowledged this in his 1837 work on the origin and nature of the United States Constitution and Government that "I am well aware of departing from the modern mode of construing our ancient charters.
"[16] Baldwin speaks on issues such as territory rights, the Articles of Confederation, State Sovereignty, Contract Cases, Definitions of A Corporation, etc.
Referring to McCulloch v. Maryland, Baldwin explains that "he has given no construction to the constitution; he has only declared what it says, by carrying out the general terms it uses, and making a practical application thereof, to the various cases, in which he has delivered the opinion of the Court.
The most complimentary of scholarly opinion on Baldwin praises his role as an "unyielding champion of the Constitution and the federal system," but at the same time labels him a "political maverick.