Henry Chang-Yu Lee (Chinese: 李昌鈺; pinyin: Lǐ Chāngyù; born 22 November 1938) is a Taiwanese and American forensic scientist.

He worked with the Taipei Police Department, where he rose to the rank of captain at age 22, the youngest in Taiwanese history.

[5][6] His biography, True Crime Experiences with Dr. Henry Chang-Yu Lee was authored by attorney Daniel Hong Deng of Rosemead, California.

A few years later when additional evidence from the hotel scene was revealed to him, Lee formally withdrew his earlier conclusion and stated, "a reconstruction is only as good as the information supplied by the police.”[9] Lee was consulted as a blood spatter analyst for defense during the trial of Michael Peterson, a fiction writer and politician from North Carolina who in 2003 was convicted of the murder of his wife, Kathleen Peterson.

In 2007, Lee testified as a prosecution expert witness at the first trial of Cal Harris, an upstate New York car dealer accused of killing his wife on the night of September 11, 2001.

Since no body has ever been found, the state's best evidence of foul play was some medium-velocity castoff impact blood spatter on the walls of the house's garage and kitchen.

In 2008, Lee was involved in the early stages of investigation in Orlando, Florida for the missing toddler Caylee Anthony.

His wife worked as a teacher and then a researcher for the United States Department of Veterans Affairs Medical Center in West Haven, Connecticut.